Comment »Posted on Friday 18 September 2009 at 10:59 am by Emma Stokes
In Biology, Health & Medicine

Yes folks, it’s that time of week again….here’s the latest from Understanding Animal Research:

How Broccoli protects arteries

C2AFE2FF-BE37-14AC-DF9E04E0F65B3A95Researchers have discovered one reason why broccoli and other green leafy vegetables are definitely good for you. Using mice, they discovered that a chemical found in these green vegetables – sulforaphane – could protect arteries from clogging, so reducing the chance of heart attacks.

Previous research has shown that certain areas of the arteries are more prone to the build up of fatty plaques. The mouse study showed that, in these areas, a protein called Nrf2 is inactive.

To read more on this story, please follow the link.

Stem cell link to prostate cancer

A new study identifies a stem cell that may cause some types of prostate cancer, at least in mice. Called CARNs (castrion-resistant Nkx2.1-expressing cells), they are responsible for creating luminal cells, which secrete chemicals into the prostate.

When they inactivated certain tumour suppressor genes in the CARN cells of mice, the team saw out-of-control growth of the luminal cells, which can lead to the formation of a tumour. The study also found that, surprisingly, the cells did not rely on male sex hormones such as androgens to thrive.

To read more on this story, please follow the link.

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